Stress makes many of us suffering — but it can also drink down you . Besides just make horrifying anxiety and depression , the physiological basis for accent has also been linked to disease as varied as obesity , postpartum depression , Cushing ’s syndrome , epilepsy , and osteoporosis . But what if we could just turn your brain ’s stress response off ?
Now , researchers from Tufts claim to have pinpointed the way that stress endocrine gain specific sensory receptor in your nous — and they ’ve even been able-bodied to block them . This could leave to the next majuscule psychopharmaceutical breakthrough .
Top image : Alex Bellink on Flickr .
The Tufts researchersdiscovered that accent nerve tract are activated by neurosteroidsacting on corticotrophin - release internal secretion neuron in what ’s know as the Hypothalamus - Pituitary - Adrenal axis vertebra . By blocking the synthesis of the neurosteroids , they cease the peak of corticosterone , and prevented anxiety in mice .
“ We have identified a novel chemical mechanism regulating the organic structure ’s response to stress by determine that neurosteroids are need to go up the physiological reply to emphasis . Moreover , we were able to completely block the physiological response to stress as well as prevent stress - bring on anxiousness , ” enunciate writer Jamie Maguire , PhD.
Now the team is focusing on modulating the neuroreceptors to treat some of the diseases that accompany stress — be they low , anxiousness , or epilepsy .
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