A Common Diabetes Drug Could Help Against Parkinson’s Disease

A newfangled study has provided more grounds suggesting that people suffering from type 2 diabetes are at higher peril of developing Parkinson ’s disease . But it also suggests that a drug usually use to deal diabetes could be employed to help foreclose Parkinson ’s .

Reporting in the journalBrain , researchers examined patient records from 100,288 people with case 2 diabetes using the UK ’s Health Improvement connection database . They found that , though most people with diabetes will not go on to develop Parkinson ’s , compared to multitude without diabetes , it does raise the jeopardy .

However , this was not the causa for mass being treat with two diabetes treatments , GLP-1 agonist ( like exenatide ) and DPP4 inhibitors . After an average follow - up time of three long time , these patient role were less potential to recrudesce Parkinson ’s compared to people taking other medication .

“ Our study has strengthened grounds that there is a data link between type 2 diabetes and Parkinson ’s disease , although it remains clear that most people with diabetes will not go on to develop Parkinson ’s , ” co - lead source Professor Tom Foltynie from University College London ( UCL ) , said in astatement .

Exenatide is currentlybeing investigatedas a potential discussion for Parkinson ’s . Anearly studyshowed that multitude that injected themselves with this diabetes - fighting drug each hebdomad for a year do better in drift run than those who injected a placebo . The research worker are now looking at go onto a Phase 3 clinical trial , project to recruit 200 people for it .

“ We have contribute to evidence that exenatide may help to foreclose or plow Parkinson ’s disease , hopefully by move the course of the disease and not merely trim symptom , but we require to progress with ourclinical trialbefore making any passport , ” Professor Foltynie contribute .

The current and future workplace exploring this avenue will be crucial in prescribing the best drug compounding for at - endangerment people .

“ It may be helpful for doctors to consider other risk factors for Parkinson ’s disease when prescribing medications for case 2 diabetes , but further inquiry will be call for to confirm clinical implications , ” co - lead author Professor Li Wei , also from UCL , explain .

In 2015 , 6.2 million the great unwashed across the world lived with Parkinson ’s , which is creditworthy for just under 120,000 deaths annually .